The cheapest Prague to Sao Paulo return flight on the radar right now is €835, flying with Air Canada via one or more connections. It covers departures in September 2027, and every dated link below opens that exact PRG–GRU search on Skyscanner. The price we usually record on this route is €803. Across 90 recorded checks it has ranged between €745 and €977. Our sampling points to September 2027 as the cheapest month to fly Prague to Sao Paulo.
Every fare here is re-confirmed against Skyscanner automatically, and each one is stamped with the moment it was last checked, so you can see how fresh it is instead of taking it on trust. Not flying from Prague? We track 60 other departure cities for Sao Paulo, listed at the foot of this page.
Fares move quickly. If this Prague to Sao Paulo price has gone by the time you search, shift the dates a day or two either side, because the same route is often still cheap just next door.