MSC Opera: Western Mediterranean Cruise from Rome to Barcelona for €297 (5 Days)

5-day Western Mediterranean cruise from Rome to Barcelona on the MSC Opera from just €297 per person in an inside cabin for two (from €357 for a cabin with a balcony). The price includes FULL BOARD (all meals included), participation in onboard events, and all port fees and taxes. In five days you sail from Italy’s capital to four more Mediterranean highlights before disembarking in Barcelona – no flights needed between stops, no packing and unpacking at every port.

Cruise at a glance

  • Ship: MSC Opera
  • Route: Rome (Civitavecchia) → Barcelona, one-way
  • Duration: 5 days / 4 nights
  • Dates: 29 October – 2 November 2026
  • Price: from €297 p.p. (inside cabin) or €357 p.p. (balcony cabin), based on 2 people sharing
  • Included: full board, onboard events, port fees and taxes

🚶 BOOK THIS CRUISE >>HERE<<

About the MSC Opera

The MSC Opera is a charming, Lirica-class ship that pairs classic Italian elegance with modern comfort. Renowned for its refined, light-filled design, it features spacious public areas, marble-accented lounges and expansive glass walls with ocean views. With a capacity of around 2,600 guests, it offers a more intimate, traditional cruising experience than today’s mega-ships – easy to navigate, yet still packed with a vibrant pool deck, a Broadway-scale theatre, a relaxing spa, and dining options ranging from formal restaurants to a casual pizzeria.

Day-by-day itinerary

Day Port Country
1 Civitavecchia (Rome) Italy
2 Genoa Italy
3 Livorno (Florence / Pisa) Italy
4 Marseille France
5 Barcelona Spain

Western Mediterranean cruise from Rome to Barcelona

cruise rome barcelona

What you’ll see at each stop

  • Civitavecchia (Rome): your gateway to the Colosseum, the Vatican and the Roman Forum, all reachable on a day trip before boarding.
  • Genoa: a historic port city with a atmospheric old town, the Genoa Aquarium and colourful Ligurian architecture.
  • Livorno: the classic jumping-off point for excursions to Florence (Renaissance art and the Duomo) or the Leaning Tower of Pisa.
  • Marseille: France’s oldest city, with the Old Port, Notre-Dame de la Garde and easy access to nearby Provence.
  • Barcelona: your final stop – explore Gaudí’s Sagrada Família and Las Ramblas before or after disembarking.

Why choose this cruise

A one-way, five-day itinerary is an efficient way to see five countries’ worth of highlights – Rome, Genoa, Tuscany, Marseille and Barcelona – without repeating a route or needing extra flights between cities.

Frequently asked questions

How much does this cruise cost?

From €297 per person in an inside cabin, or €357 per person for a cabin with a balcony, based on two people sharing.

What is included in the price?

Full board (all meals), participation in onboard events, and all port fees and taxes.

Which ports does the cruise visit?

Civitavecchia (Rome), Genoa, Livorno (for Florence/Pisa), Marseille, and Barcelona, over 5 days / 4 nights.

What ship operates this cruise?

The MSC Opera, an MSC Cruises Lirica-class ship carrying around 2,600 guests.

When does this cruise depart?

29 October to 2 November 2026, departing from Rome (Civitavecchia) and ending in Barcelona.

Where can I book this cruise?

Via e-hoi.de – the site is in German, so use Google Translate if needed.

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